Hypertensive Nephropathy (Root Deficiency with Manifestation Excess Pattern)

Hypertensive nephropathy is a disease caused by primary hypertension, characterized by benign arteriolar nephrosclerosis (also known as hypertensive renal arteriolosclerosis) or malignant arteriolar nephrosclerosis, together with corresponding clinical manifestations.
In traditional Chinese medicine (TCM), hypertensive nephropathy is generally classified under categories such as “dizziness,” “low back pain,” “consumptive illness,” and “edema.”

TCM Pattern Differentiation and Medication Reference

|Common Symptoms

Clinical description:

Urine is pale red, with little noticeable pain or difficulty during urination; soreness and weakness in the lower back and knees, fatigue, a pale-red tongue with little coating, and a fine, rapid pulse.

Plain-language explanation:

  • The urine may look light red, with a noticeable but not deep-red color.
  • Pain, a stinging sensation, or difficulty when urinating is not very noticeable or severe.
  • The lower back may feel sore, and the knees may feel weak; this can be more noticeable with activity or after sitting for a long time.
  • You may feel tired and lacking in energy, with little improvement after resting.
  • The tongue may be pale red in color.
  • There may be very little coating on the tongue, with almost no obvious thick coating.
  • The pulse may feel fine and fast, with a rapid rhythm and a fine, light quality when pressed.

|Treatment Approach

Clinical description:

Nourish yin, clear heat, and replenish kidney essence.

Plain-language explanation:

  • Nourish yin fluids in the body to support balance between yin and yang and ease signs of deficiency heat, restlessness, or night sweats.
  • Clear deficiency heat, which may help ease symptoms such as thirst, insomnia, or hot flashes.
  • Nourish kidney essence to help ease soreness and weakness in the lower back and knees and feelings of fatigue.
  • Support the replenishment of essence and qi, with the aim of improving vitality and gradually restoring well-being.

|Related Products

The products below are provided for informational reference only and do not constitute medical advice or a prescription. Refer to the product packaging and instructions, and use under the guidance of a physician or pharmacist.

|Common Symptoms

Clinical description:

Dizziness and tinnitus, numbness and tremors in the limbs, headache, a red tongue with a yellow coating, and a wiry pulse.

Plain-language explanation:

  • You may feel dizzy or lightheaded and have tinnitus—a buzzing or ringing sound that can be heard even in quiet surroundings. A floating sensation when walking may be more noticeable.
  • The limbs may feel numb and have slight tremors, which may be more noticeable during activity or when tense.
  • You may have a persistent headache that feels worse with concentration or prolonged visual tasks and interferes with daily activities.
  • The tongue may appear red, with a yellow coating.
  • The pulse may feel tense and straight, like a taut string, rather than soft and relaxed.

|Treatment Approach

Clinical description:

Calm the liver and anchor yang; nourish the liver and kidneys.

Plain-language explanation:

  • Help calm excessive liver yang, which may ease dizziness, headaches, or irritability.
  • Help restrain upward-rising deficient yang, which may ease insomnia, tinnitus, or facial flushing.
  • Nourish the liver and kidneys to support adequate essence and blood, which may help with blurred vision and soreness or weakness in the lower back and knees.
  • Support coordination between the liver and kidneys and balance between yin and yang as part of an overall approach to well-being.

|Related Products

The products below are provided for informational reference only and do not constitute medical advice or a prescription. Refer to the product packaging and instructions, and use under the guidance of a physician or pharmacist.

|Common Symptoms

Clinical description:

Fatigue and weakness, soreness and weakness in the lower back and knees, skin bruising, prominent superficial veins, rough, scaly skin, a red or pale tongue, and a fine, weak pulse, or a deep, hesitant pulse.

Plain-language explanation:

  • You may feel tired and weak, with little energy for tasks and limited improvement after rest.
  • The lower back and knees may feel sore and weak, with a sense of reduced strength when walking or sitting for a long time.
  • Dark purplish bruises may appear on the skin, like small spots or patches of bleeding under the skin.
  • Superficial veins may be prominent, with their paths clearly visible and raised in appearance.
  • The skin may be dry and rough to the touch, with an uneven, fish-scale-like appearance.
  • The tongue may appear red or pale.
  • The pulse may feel fine and weak, or be palpable only with deeper pressure and feel hesitant or uneven.

|Treatment Approach

Clinical description:

Nourish yin and clear heat, invigorate blood and resolve stasis, and boost qi to support the kidneys.

Plain-language explanation:

  • Nourish yin fluids and clear deficiency heat, which may ease thirst, hot flashes, or restlessness.
  • Support blood circulation and help disperse blood stasis, which may ease pain, numbness, or bruising.
  • Support energy and nourish kidney qi, which may help with soreness and weakness in the lower back and knees, fatigue, or night sweats.
  • Support balance between yin and yang and the gradual restoration of energy and physical stamina.

|Related Products

The products below are provided for informational reference only and do not constitute medical advice or a prescription. Refer to the product packaging and instructions, and use under the guidance of a physician or pharmacist.

|Common Symptoms

Clinical description:

Edema, headache with dizziness, nausea and vomiting, aversion to cold, and fatigue in the limbs.

Plain-language explanation:

  • Swelling may occur, making the skin look puffy and tight; the swelling may be noticeable when pressed.
  • You may have a headache along with dizziness, and feel less steady when active or concentrating.
  • You may feel nauseated and want to vomit; vomiting may occur, and you may still feel unwell afterward.
  • You may feel cold and have tired, weak limbs, with low energy and difficulty standing for a long time.

|Treatment Approach

Clinical description:

Tonify the spleen and benefit the kidneys; transform dampness and reduce turbidity.

Plain-language explanation:

  • Support spleen function to help digestion and absorption and support energy levels.
  • Nourish the kidneys and support kidney essence, which may ease soreness and weakness in the lower back and knees and feelings of fatigue.
  • Support the removal of dampness from the body, which may help with feelings of heaviness, tiredness, or swelling.
  • Help transform turbidity, which may ease symptoms such as dizziness, a sticky feeling in the mouth, or a heavy feeling in the body.

|Related Products

The products below are provided for informational reference only and do not constitute medical advice or a prescription. Refer to the product packaging and instructions, and use under the guidance of a physician or pharmacist.

|Common Symptoms

Clinical description:

Dizziness and lightheadedness, fatigue in the limbs, soreness and weakness in the lower back and knees, a pale tongue with a white coating, and a fine, weak pulse.

Plain-language explanation:

  • You may feel dizzy or lightheaded and unsteady when standing or walking; this may be more noticeable after activity.
  • The limbs may feel tired and weak, with little energy for tasks and difficulty fully recovering after rest.
  • The lower back and knees may feel sore and weak, with a sense of poor support or reduced strength when walking or sitting for a long time.
  • The tongue may look pale and have a white coating.
  • The pulse may feel fine and weak, with a light, faint quality when pressed.

|Treatment Approach

Clinical description:

Boost qi and nourish blood; transform phlegm and reduce turbidity.

Plain-language explanation:

  • Support energy levels, which may help ease fatigue and weakness and gradually restore a sense of well-being.
  • Nourish the blood to support a healthy-looking complexion and vitality.
  • Help transform phlegm and turbidity in the body, which may ease symptoms such as excess phlegm, chest tightness, or a heavy feeling in the head.
  • Help reduce turbidity, which may ease discomfort such as lightheadedness, a sticky feeling in the mouth, or heaviness and fatigue.

|Related Products

The products below are provided for informational reference only and do not constitute medical advice or a prescription. Refer to the product packaging and instructions, and use under the guidance of a physician or pharmacist.

|Common Symptoms

Clinical description:

Thirst, shortness of breath, dizziness and tinnitus, increased appetite and easy hunger, fatigue, soreness and weakness in the lower back and knees, a red or pale tongue, and a fine, weak pulse.

Plain-language explanation:

  • You may often feel thirsty and want to drink water, but drinking may only temporarily relieve the dryness.
  • You may become short of breath easily and feel that you do not have enough breath or strength after even mild activity.
  • You may feel dizzy and have tinnitus, a buzzing sound that can be heard even in quiet surroundings; you may feel less steady when standing.
  • You may eat a lot but feel hungry again soon, wanting to eat again not long after a meal.
  • You may feel tired and weak, with little energy for tasks and limited improvement after resting.
  • The lower back and knees may feel sore and weak, with a sense of reduced support when walking or sitting for a long time.
  • The tongue may appear red or pale.
  • The pulse may feel fine and weak, and may be easier to detect with steady pressure.

|Treatment Approach

Clinical description:

Boost qi and nourish yin, tonify the kidneys and strengthen the spleen, and clear residual toxins.

Plain-language explanation:

  • Support energy and nourish yin fluids, with the aim of gradually restoring energy and physical stamina.
  • Nourish the kidneys and spleen to support digestion and absorption and help ease soreness and weakness in the lower back and knees and feelings of fatigue.
  • Clear residual pathogenic factors in the body, which may ease symptoms such as dry mouth, sore or swollen throat, or sores.

|Related Products

The products below are provided for informational reference only and do not constitute medical advice or a prescription. Refer to the product packaging and instructions, and use under the guidance of a physician or pharmacist.

  1. Ministry of Health of the People’s Republic of China. Guiding Principles for Clinical Research on New Traditional Chinese Medicines [S]. Beijing: People’s Medical Publishing House, 2002: 156–162.
  2. Kidney Disease Branch of the China Association of Chinese Medicine. Diagnosis, pattern differentiation and classification, and efficacy assessment of chronic renal failure (trial scheme) [J]. Shanghai Journal of Traditional Chinese Medicine, 2007, 4(8): 8–9.
  3. Wang Yong, Jiang Zhenghui. Handbook of Practical Chinese Patent Medicines [M]. Xi’an: Fourth Military Medical University Press, 2007.
  4. Zhou Zhongying. Internal Medicine of Traditional Chinese Medicine [M]. 2nd ed. Beijing: China Press of Traditional Chinese Medicine, 2008.
  5. Xu Liping. Handbook of Practical Chinese Patent Medicines [M]. Beijing: China Press of Traditional Chinese Medicine, 2010.
  6. Yang Peimin, Sun Hongsheng, Yao Li. Handbook of New Chinese Patent Medicines [M]. Shandong: Shandong Science and Technology Press, 2014.
  7. Cai Yanfang, Chen Zhiling, Zhang Lifen. Clinical observation of the efficacy of Songling Xuemaikang in treating primary hypertension [J]. Guide of China Medicine, 2011, 9(30): 339–341.
  8. Zhou Jingrong. Tianma Gouteng Granules combined with commonly used Western medicines for the treatment of hypertension in older adults [J]. Chinese Journal of Experimental Traditional Medical Formulae, 2013, 19(7): 327–328.
  9. Liu Ye, Luo Donghua, Jiang Huiqian. Clinical observation of Tianma Gouteng Granules combined with captopril in treating 63 cases of primary hypertension [J]. Guiding Journal of Traditional Chinese Medicine and Pharmacy, 2014, 20(13): 73–75.
  10. Wu Chunxia, Jia Xi. Preliminary study of the efficacy of Tianma Gouteng Granules in treating hypertension in women during menopause [J]. Medical Information, 2010, 23(12): 4582–4584.
  11. Guo Xibao, Xing Guang. Overview of the treatment of hypertension with Chinese patent medicines [J]. Journal of Practical Traditional Chinese Internal Medicine, 2013, 27(5): 159–161.
  12. Wang Lingchun. Clinical observation of integrative Chinese and Western medicine treatment for early renal damage in primary hypertension [J]. Journal of Nanjing University of Traditional Chinese Medicine, 2005, 21(6): 366–367.
  13. Ma Zebin, Chen Guangliang, Zhu Keke. Research progress on the prevention and treatment of hypertensive nephropathy with Chinese medicine [J]. Chinese Journal of Ethnomedicine and Ethnopharmacy, 2016, 12: 27.