An Zhong San
Overview
An Zhong San originated in the Song dynasty work Taiping Huimin Hejiju Fang. It is a classic formula that warms the Middle and disperses Cold to relieve pain, with actions of warming the Middle, dispersing Cold, regulating Qi, and relieving pain. It is mainly used for gastric pain, acid regurgitation, abdominal distension, nausea, and unresolved food accumulation caused by Cold accumulation in the Spleen and Stomach and impeded Qi movement. It was later introduced to Japan and became one of the commonly used Kampo formulas.

Formula Composition
Common ingredients include cinnamon bark, Corydalis tuber, oyster shell, fennel, Amomum fruit, licorice, and galangal.
Note: The proportions of ingredients may vary among preparations from different manufacturers and regions. Refer to the instructions for the actual product.
Traditional Actions and Indications
In modern Kampo practice, it is commonly used according to pattern differentiation for chronic gastrointestinal symptoms such as a constitution tending toward Cold, dull gastric pain or burning discomfort, acid reflux, nausea, and poor appetite.
Precautions
- Persistent stomach pain, difficulty swallowing, vomiting blood, black stools, or unexplained weight loss require prompt medical attention.
- Acute severe abdominal pain or fever should not be managed solely with this formula.
- With long-term use of licorice-containing preparations, monitor for edema and changes in blood pressure and electrolytes.
- Pregnant individuals, children, and people with chronic illnesses are advised to consult a qualified professional before use.
